Information about Accutane

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Accutane (commonly known as Isotretinoin) is a Vitamin A derivative known as a Retinoid which works by altering the amount of oil or “sebum” produced by your skin’s sebaceous glands. By controlling the amount of sebum produced in your skin, acne-causing bacteria, which feed on the oil and dirt on your skin, become inhibited and can no longer grow. Over time, Accutane’s effects become noticeable and in most cases acne can be effectively treated in 4-6 months.

Isotretinoin was originally patented as a chemotherapy medication because of its ability to control cellular growth in epithelial cells, particularly in the pancreas, leukocytes, the brain, and other locations. As clinical trials advanced, it became apparent that the medication was extremely effective for treating severe forms of acne. After product testing, Accutane was approved by the FDA and quickly released to the public in 1982 to treat severe, nodular, cystic acne.

Since 1982, Accutane and its generic versions have become increasingly popular among doctors and dermatologists because of its efficiency in treating acne, which in turn has translated into an enormous number of prescriptions given along with an anticipated high number of people negatively impacted by its use. However, because of its efficacy, its use has grown to include milder cases of acne in patients who may not know about the severe side effects the medication can produce. The product label warns that Accutane is to be used only after other forms of skin therapy, such as topical creams and antibiotics, have failed.