Accutane Side Effects
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Accutane and teratogenic birth defects during pregnancy:
The main warning involving Accutane describes the teratogenic birth defects which impinge on a large number of patients who become pregnant while taking Accutane. Roche has taken numerous steps to try and minimize the risk of patients becoming pregnant while on Accutane. Some examples of Roche’s initiatives include its national iPLEDGE program which involves asking patients to sign documentation, offering reading materials for patients, and emphasizing that patients should use two forms of contraception while taking Accutane.
Other side effects of the drug include:
Inflammatory bowel disease*, nausea, pancreatitis, diarrhea, abdominal pain, rectal bleeding, fragile/dry skin and nails, higher risk of sunburn, joint pain, vision problems (decreased night vision, cataracts), dry eyes, hyperostosis (abnormal bone growth), calcified tendons, liver damage, depression, suicide, psychosis, aggression, cheilitis (dry, inflamed lips), bone loss, raised triglyceride levels, hearing impairment, hair loss, epiphyseal closure (closing of growth plates), spondylothesis, back pain, headache, stroke, dizziness, and seizures.