Frequently Asked Questions
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What conditions are treated by Isotretinoin?
- Severe recalcitrant nodular cystic acne that is not responsive to other therapy.
- Some doctors also may have prescribed the drug to treat off-label conditions other than acne, such as a chemotherapy agent for specific types of cancer.
IBD is an encompassing condition which groups together two diseases; Crohn's Disease and Ulcerative Colitis. IBD involves inflammation taking place within the colon and small intestine which can cause abdominal pain, severe diarrhea and rectal bleeding.
Is inflammatory bowel disease (IBD) different from irritable bowel syndrome (IBS)?
- Inflammation of the colon lining is the key difference when describing the two GI tract disorders.
- IBS can be described as a change in bowel function, or an abnormal communication path affecting how the bowels interact with the brain. Inflammation does not play a role for IBS sufferers; however, IBS may also exist among people diagnosed with IBD.
What actions have been taken by regulatory agencies?
- The FDA has created detailed brochures describing how Accutane can cause birth defects. Since 2005, in the United States, Accutane customers must sign a consent form known as the “iPledge program” which promises that the patient will take birth control while using Accutane in order to minimize the possibility of birth defects.
Is Accutane still available to people suffering from severe, cystic, nodular acne?
- Yes, Isotretinoin is still available in Canada and the U.S. but is no longer manufactured by Hoffmann-La Roche.
- The drug is manufactured by generic companies and is available under brand names such as Sotret, Clarus, Amnesteen, Claravis, and others.
How long does it take to develop IBD after taking Accutane?
- Some patients have reported experiencing symptoms while they are still on the drug or soon after they stopped taking it.
- Some patients report that they have “flares” of their symptoms if they go back on Accutane after taking a break from using the drug.
- Other patients have reported symptoms developing months and years after taking Isotretinoin.